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PFA at Eurotox 2015 in Porto, Portugal

October 19th, 2015

This year’s Eurotox conference was held in September in the idyllic city of Porto in Portugal, and covered a range of important issues ongoing in current regulatory toxicology. A team from PFA were among over 1500 delegates in attendance at this important annual event. Regulatory assessment best practice and ethical approaches were among the most important topics. A broad range of lectures were delivered and posters were exhibited during the four day event.

The relevance of alternative methods in toxicology and their role in driving forward the implementation of the ‘3Rs’ (replacement, reduction, refinement) and the more ethical use of animals in hazard assessment were some of the key issues brought forward in the event. The ‘antibiotic crisis’ and disorders of the gut microbiome and their association with various prominent disease states was also given a spotlight. A series of informative lectures on perspectives in Substance Evaluation in REACH outlined the dynamics of the evolving landscape and summarised well the experiences so far. PFA, as a consultancy serving both industrial and regulatory clients, found the breadth of experience gained so far well reflected in these talks.

The number of substance evaluations is expected to grow considerably in the coming years, and anticipated to have a major impact on the safe use of chemicals in the EU. This enforced the notion that follow-up work on submitted REACH dossiers will continue to be a major aspect of EU regulatory work.

Other topics which were discussed included: the future direction of improving the assessment of endocrine disruptors through developing testing strategies; mixtures assessment and the importance of toxicokinetic models in advancing understanding of chemical risk assessment as well as supporting the reduction of animal testing, an important objective for the chemical safety sector.